Nema- Home for Golden Years

 Alzheimer’s Disease is the most common form of dementia and has shown an incidence of 11.67 per 1000 persons less than or equal to 55years of age. In India, more than 4 million people are estimated to be suffering from Alzheimer’s and other forms of dementia, giving the country the third highest caseload in the world, after China and the US. It is challenging to deal with patients with Alzheimer’s disease because of its severe health complications. It is a neurodegenerative disease that is a progressive form of dementia. It gradually worsens as the disease advances. According to the Alzheimer’s Association, Alzheimer’s disease accounts for 60 to 80 percent of dementia cases. Most people with the disease get a diagnosis after age 65. If it’s diagnosed before, it’s generally referred to as early-onset Alzheimer’s disease. Alzheimer’s disease causes and risk factors Alzheimer’s disease affects the elderly, I.e., Above the age of 65 years. It can be a genetic or hereditary disorder. Y...

 Some form of dementia-like frontotemporal dementia can show early symptoms at 40. Frontotemporal dementia, or frontotemporal lobar dementia, is an umbrella term that refers to a range of early-onset dementias characterized by the progressive atrophying of the brain’s frontal lobes, temporal lobes, or both. Cognitive function impairments and personality and behavioral changes, difficulty in writing, and speaking are the significant symptoms of this kind of dementia. They are mostly genetic or hereditary. Studies suggest a genetic mutation that prevents brain cells from making a protein called progranulin. The absence of Progranulin is associated with this kind of dementia. The role of antibiotics  The brain cells that are mutated and show an absence of progranulin synthesis, in the presence of antibiotics, 'trick' the cellular machinery into making it. The researchers found two specific aminoglycoside antibiotics -- Gentamicin and G418 -- were influential in fixing the mutatio...